Endothelial Nitric Oxide Production (The most important for athletes) relies on the enzyme eNOS to convert Arginine amino acid to Nitric Oxide.
Contains nitrate, natural nitrate is converted to nitrite by bacteria on the tongue and then further in the stomach. As nitrite enters the bloodstream it is converted to nitric oxide.
Pycnogenol is effective in aiding nitric oxide production. When consumed it activates eNOS in your body and is a catalyst to rapid Nitric Oxide Production. It also has several other imperative functions for performance and recovery as it is a free radical scavenger which reduces oxidative stress caused by training and extends the life of NO in the body.
NO PATHWAY COMPARISONS
Pycnogenol > eNOS > Nitric Oxide in blood
eNOS is found in the body in limited amounts, Therefore, only so much NO can be generated at any one time Pycnogenol acts on the endothelial cells (most important) in the blood vessels to switch on the synthesis of eNOS
More eNOS = More NO generated
Pycnogenol also nuetralization free radicals caused by exercise which ensures NO molecules remain stable, prolonging its availability (maintains greater levels)
Beet Juice > Nitrate > Nitrite > Nitric Oxide in tissues
Nitrate needs to convert to Nitrite by bacteria on the tongue and then in the stomach Nitrite then needs an acidic environment to be efficiently converted to NO. NO is mostly converted in the tissues of the heart and the liver and not efficiently in the blood or by endothelial cells where its is most needed for better blood flow.